Previous ISAC webinars have discussed the major impact on health caused by the COVID-19 pandemic. Despite rapid global efforts to develop diagnostics and treatments, sequence COVID strains and the huge achievement to develop and deploy effective vaccines, there are aspects of the underlying disease that remain poorly understood. Millions of patients with COVID (possibly 1 in 5) report symptoms lasting more than four weeks. This webinar will explore long COVID which may represent several syndromes including post-viral fatigue, lasting organ damage or post-intensive care symptoms; its pathology, immunology and impact.